منابع مشابه
Hitchhiking Through the Cytoplasm
We propose an alternative mechanism for intracellular cargo transport which results from motor-induced longitudinal fluctuations of cytoskeletal microtubules (MTs). The longitudinal fluctuations combined with transient cargo binding to the MTs lead to long-range transport even for cargos and vesicles having no molecular motors on them. The proposed transport mechanism, which we call “hitchhikin...
متن کاملThe "hitchhiking effect" revisited.
The number of selectively neutral polymorphic sites in a random sample of genes can be affected by ancestral selectively favored substitutions at linked loci. The degree to which this happens depends on when in the history of the sample the selected substitutions happen, the strength of selection and the amount of crossing over between the sampled locus and the loci at which the selected substi...
متن کاملHitchhiking to Speciation
The modern evolutionary synthesis codified the idea that species exist as distinct entities because intrinsic reproductive barriers prevent them from merging together. Understanding the origin of species therefore requires understanding the evolution and genetics of reproductive barriers between species. In most cases, speciation is an accident that happens as different populations adapt to dif...
متن کاملHitchhiking without Covalent Integration
In eukaryotes, many latent viruses attach to mitotic chromosomes noncovalently for effective partitioning in dividing cells. For different viruses, the cis and trans elements encoded by the episomes have been effectively defined but the chromosomal "receptors" for such tethering have remained elusive. In this issue of Cell, give us a first insight into the cellular protein machinery important f...
متن کاملDistinguishing the hitchhiking and background selection models.
A simple method to distinguish hitchhiking and background selection is proposed. It is based on the observation that these models make different predictions about the average level of nucleotide diversity in regions of low recombination. The method is applied to data from Drosophila melanogaster and two highly selfing tomato species.
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ژورنال
عنوان ژورنال: Europhysics Letters (EPL)
سال: 2007
ISSN: 0295-5075,1286-4854
DOI: 10.1209/0295-5075/81/18001